Relieve aches, pains, and tough headaches with fast-acting, extra-strength headache medicine from ValuMeds.

When you're looking for an advanced pain reliever that combines the very best of acetaminophen, as...

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Relieve aches, pains, and tough headaches with fast-acting, extra-strength headache medicine from ValuMeds.

When you're looking for an advanced pain reliever that combines the very best of acetaminophen, aspiring, and caffeine, look no further than extra-strength ValuMeds headache medicine.

Offering the active ingredients found in Excedrin, our advanced pain relief caplets can start providing essential relief in as little as 15 minutes. Safe, effective, and with just a small caffeine boost to help restore your clarity and focus, this anti-inflammatory and pain reliever is perfect for arthritis, sore muscles, aching joints, menstrual cramping, and more.

Product Details:

  • Headache Medicine and Pain Reliever
  • Acetaminophen (250mg)
  • Aspirin (250mg) NSAID
  • Caffeine (65mg)
  • Nonsteroidal Anti-Inflammatory
  • Safe, Effective Support
  • Volume: 300 Caplets
  • Safety Note: Please adhere to all safety warnings provided. Always consult your doctor prior to using any medicines.

Click 'Add to Cart' to start relieving headaches and muscle aches and pains with extra-strength support from ValuMeds.



  • 🔴 Fast-Acting, Triple-Ingredient Formula for Maximum Relief: Each caplet contains acetaminophen 250 mg, aspirin 250 mg, and caffeine 65 mg to work together for powerful headache, migraine, and body pain relief. This trio of active ingredients tackles inflammation, boosts pain tolerance, and improves blood flow—ideal for tension headaches, sinus headaches, and migraine symptoms.
  • 💊 Generic Equivalent to Excedrin Extra Strength: Get the same effective relief as Excedrin, Tylenol, Equate, or Anacin Extra Strength, at a fraction of the price. Whether you're looking for generic Excedrin Migraine or Gencare Extra Strength, ValuMeds is your go-to budget-friendly option.
  • 🧠 Migraine Support When You Need It Most: Trusted by millions of happy customers, this non-prescription migraine medication is ideal for managing symptoms such as sensitivity to light, throbbing pain, and nausea. Use as directed to catch migraines early and reduce the duration and intensity of your attacks.
  • 💪 Extended Relief for Muscle, Joint, and Arthritis Pain: This isn’t just a headache pill, it’s an extra strength pain reliever formulated to handle more than migraines. Use it to ease back pain, sore joints, inflammation, and arthritis flare-ups caused by overexertion or chronic conditions.
  • ☑️ Accessible Pain Relief with Caffeine: Caffeine is a proven ingredient in pain relief pills, helping to amplify the effects of acetaminophen and aspirin while improving circulation and focus. That’s why it’s included in many headache medicine formulas for adults and why it works fast.
  • 🧴 Value Bottle 300 Caplets for Long-Term Relief: Whether you take headache medicine occasionally or rely on it daily, this large-count bottle ensures you’ll have plenty on hand. A great choice for home, travel, or office use, especially when you're tired of paying more for fewer pills.
  • 🔴 Fast-Acting, Triple-Ingredient Formula for Maximum Relief: Each caplet contains acetaminophen 250 mg, aspirin 250 mg, and caffeine 65 mg to work together for powerful headache, migraine, and body pain relief. This trio of active ingredients tackles inflammation, boosts pain tolerance, and improves blood flow—ideal for tension headaches, sinus headaches, and migraine symptoms.
  • 💊 Generic Equivalent to Excedrin Extra Strength: Get the same effective relief as Excedrin, Tylenol, Equate, or Anacin Extra Strength, at a fraction of the price. Whether you're looking for generic Excedrin Migraine or Gencare Extra Strength, ValuMeds is your go-to budget-friendly option.
  • 🧠 Migraine Support When You Need It Most: Trusted by millions of happy customers, this non-prescription migraine medication is ideal for managing symptoms such as sensitivity to light, throbbing pain, and nausea. Use as directed to catch migraines early and reduce the duration and intensity of your attacks.
  • 💪 Extended Relief for Muscle, Joint, and Arthritis Pain: This isn’t just a headache pill, it’s an extra strength pain reliever formulated to handle more than migraines. Use it to ease back pain, sore joints, inflammation, and arthritis flare-ups caused by overexertion or chronic conditions.
  • ☑️ Accessible Pain Relief with Caffeine: Caffeine is a proven ingredient in pain relief pills, helping to amplify the effects of acetaminophen and aspirin while improving circulation and focus. That’s why it’s included in many headache medicine formulas for adults and why it works fast.
  • 🧴 Value Bottle 300 Caplets for Long-Term Relief: Whether you take headache medicine occasionally or rely on it daily, this large-count bottle ensures you’ll have plenty on hand. A great choice for home, travel, or office use, especially when you're tired of paying more for fewer pills.

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