Ornithine is a non-essential amino acid derived from the breakdown of arginine during the citric acid cycle. It helps build lean muscle and reduce body fat, especially when combined with the amino acids arginine and carnitine. Ornithine is also needed for the formation of citrulline, proline, and glutamic acid, three amino acids that help supply energy to every cell in the body. Laboratory studies have shown that ornithine increases both insulin and growth hormone levels, which are needed to build and maintain muscle during intensive physical training. Ornithine may also help combat the muscle loss that is a normal part of the aging process. As the body ages, it is unable to regenerate muscle tissue as quickly, so strength and muscularity begin to decline. By helping to elevate growth hormone levels, ornithine may help speed the growth of muscle tissue and offset the effects of aging. Ornithine is generally thought to be twice as effective at stimulating growth hormone production as arginine, so a combination of both is not necessary if you wish to use ornithine for this purpose. Ornithine helps remove toxic ammonia from the liver, and may reduce the effects of disorders associated with liver malfunction. In one study, participants taking 18 grams of ornithine for two weeks showed significant improvement in blood tests and liver function compared to the placebo group. Research has also shown that ornithine helps promote healing and tissue repair. L-Ornithine is a non-essential amino acid that is an important intermediate in the urea cycle, functioning along with Arginine to rid the body of ammonia, a byproduct of protein metabolism. Both Ornithine and Arginine are known to support the production of Nitric Oxide (NO). NO plays a fundamental role in vascular function and blood flow. Ornithine therefore, not only supports detoxification pathways, but also supports NO production and a healthy cardiovascular system.